Bipolar disorder and alcoholism: Are they related?

Effects of Alcohol on Bipolar Disorder

Understanding bipolar dual diagnosis is the first step towards effective treatment. Many mental health facilities now offer specialized programs for individuals with co-occurring disorders, providing integrated treatment that addresses both conditions simultaneously. In a pioneer work, van Gorp et al. (1998) examined 12 BD patients with past history of alcohol dependence, 13 BD patients without such comorbidity, and 22 healthy controls.

Combination of Bipolar Disorder and Alcohol

  1. Bipolar disorder (BD) and alcohol use disorder (AUD) are independently a common cause of significant psychopathology in the general population.
  2. The potential relevance of systems medicine for AUD (Spanagel et al., 2013; Gorini et al., 2014) and BD (Frangou, 2014; McIntyre et al., 2014) has been recently proposed.
  3. An outpatient program doesn’t necessarily have the resources or experts to address all of your needs.
  4. Almost all drugs that are misused — from nicotine to opioids — target a an area of the brain called the nucleus accumbens.

Health care providers may recommend behavioral therapies alone or in combination with medications. During withdrawal from heavy drinking, people may develop delirium tremens, a complication of withdrawal marked by psychotic symptoms, such as hallucinations (see Core article on AUD). As with anxiety and mood disorders, it can help for a healthcare professional to create a timeline with the patient to clarify the sequence of the traumatic event(s), the onset of PTSD symptoms, and heavy alcohol use.

Effects of Alcohol on Bipolar Disorder

Co-occurring conditions

However, the clinical groups were not balanced regarding gender, educational level and number of hospitalizations, so a potential influence of these relevant variables on neurocognitive results cannot be entirely ruled out. Bipolar disorder and alcohol problems seem to go hand-in-hand, leading to a widespread belief that drinking acts as a kind of “self medication” to ease bipolar’s life-altering symptoms of mania, depression, anxiety, sleep disturbances and more. One of how to identify liberty caps the most pressing questions for individuals with bipolar disorder and their loved ones is whether alcohol makes bipolar disorder worse. The short answer is yes, alcohol can significantly exacerbate bipolar symptoms and interfere with treatment efficacy. Another reason is that people with bipolar disorder often self-medicate to manage their mental health condition. SAMHSA reports that people with bipolar disorder tend to have a higher risk for substance use disorders.

Rethinking Drinking: Tools

A dual diagnosis is when someone is diagnosed with a substance use disorder (SUD) and mental health disorder. Many people with bipolar disorder turn to alcohol to self-medicate and reduce symptoms. While they may find temporary relief, alcohol increases the severity of symptoms over time. To receive a bipolar 2 disorder diagnosis, you must have had at least one major depressive episode. The combination of bipolar disorder and AUD can have severe consequences if left untreated. People with both conditions are likely to have more severe symptoms of bipolar disorder.

Depression After Quitting Drinking: Understanding and Overcoming the Challenges

Alcohol use can significantly complicate the course of bipolar disorder, leading to more frequent hospitalizations, increased suicide risk, and poorer overall outcomes. If you have bipolar disorder, partaking in substances may feel good at the moment, but they can end up causing negative health effects in the long run. According to the National Institute of Mental Health (NIMH), almost half of people with substance use disorder also have a mental health condition. If the AUD commences before the BD, then one hypothesis for the comorbidity would be that the AUD activates a predisposition towards BD in that subgroup; although there is no genetic or familial evidence for this (Maier and Merikangas, 1996). The other hypothesis, namely that patients with BD use alcohol to self-medicate their mood symptoms, or drink a result of their tendency towards impulsive behaviours, may also apply (Swann et al., 2003). It is likely, however, that within the spectrum of comorbid AUD and BD, there lies a variety of orders and associations, and that no one hypothesis explains the full spectrum of presentations.

One proposed explanation is that certain psychiatric disorders (such as bipolar disorder) may be risk factors for substance use. Alternatively, symptoms of bipolar disorder may emerge during the course of chronic alcohol intoxication or withdrawal. Still other studies have suggested that people with bipolar disorder may use alcohol during manic episodes in an attempt at self-medication, either to prolong intermediate familial subtype their pleasurable state or to sedate the agitation of mania. Finally, other researchers have suggested that alcohol use and withdrawal may affect the same brain chemicals (i.e., neurotransmitters) involved in bipolar illness, thereby allowing one disorder to change the clinical course of the other. In other words, alcohol use or withdrawal may “prompt” bipolar disorder symptoms (Tohen et al. 1998).

Alcohol may also aggravate bipolar disorder neuro-progression via oxidative stress. Allostatic changes in the brain reward system may render BD patients more vulnerable to drug addiction. Patients with AUD-BD comorbidity show earlier onset, a more severe course of illness, higher impulsivity levels, worse treatment response, and increased suicide risk compared to patients with BD alone.

There are a number of pharmacotherapy trials, and psychotherapy trials that can aid programme development. Post-treatment prognosis can be influenced by a number of factors including early abstinence, baseline low anxiety, engagement with an aftercare programme and female gender. The future development of novel therapies relies upon increased psychiatric and medical awareness of the co-morbidity, and further research into novel therapies for the comorbid group.

Alcohol use disorder is a chronic, lifelong, relapsing illness undermining happiness, work, relationships, and free will. The NIMH Strategic Plan for Research is a broad roadmap for the Institute’s research priorities over the next five years. Learn more about NIMH’s commitment to accelerating the pace of scientific progress and transforming mental health care. Learn about NIMH priority areas for research and funding that have the potential to improve mental health care over the short, medium, and long term.

Drugs release excessive amounts of a chemical called dopamine in this region to create pleasurable effects. In BD, there is an equal incidence of men and women, emphasising the genetic origin of the disorder. In AUD, while there is a higher incidence in men, the genetic component may be more prominent in women (Kendler et al., 1992). There are neurochemical abnormalities in both disorders in the serotonin/dopamine pathways, which could suggest a similar pathology in both disorders (Yasseen et al., 2010).

Bipolar disorder, a mental health condition characterized by extreme mood swings, affects millions of people worldwide. When combined with alcohol consumption, the consequences can be particularly challenging and even dangerous. Understanding the interplay between these two factors is crucial for those living with bipolar disorder, their loved ones, and healthcare professionals alike. Liquid courage meets mental mayhem as we dive into the perilous dance between alcohol and bipolar disorder, where every sip can tip the scales of an already delicate emotional balance. The intricate relationship between alcohol consumption and bipolar disorder is a complex and often misunderstood topic that deserves careful examination. As we explore this subject, we’ll uncover the potential risks, effects, and management strategies that individuals with bipolar disorder should consider when it comes to alcohol use.

Bipolar II disorder has episodes of depression and hypomanic episodes but no mania. A person is more likely to seek treatment during a depressive episode than a manic episode. About 45 percent of people with bipolar disorder also have alcohol use disorder (AUD), according to a 2013 review. There is also a greater risk of suicide in individuals who have bipolar disorder and alcohol use disorder.

Some evidence is available to support the possibility of familial transmission of both bipolar disorder and alcoholism (Merikangas and Gelernter 1990; Berrettini et al. 1997). Common genetic factors may play a role in the development of this comorbidity, but this relationship is complex (Tohen et al. 1998). Preisig and colleagues (2001) conducted a family how to wean off alcohol safely study of mood disorders and alcoholism by evaluating 226 people with alcoholism with and without a mood disorder as well as family members of those people. The researchers found that there was a greater familial association between alcoholism and bipolar disorder (odds ratio of 14.5) than between alcoholism and unipolar depression (odds ratio of 1.7).

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